Pep Guardiola’s side are in a rich vein of form, and will be looking to close the gap on the top of the table with a win.
City have had a plethora of absences in recent weeks, but should have a number of key talents back in contention for a starting spot against the Seagulls.
In a press conference on Tuesday, the Spanish boss confirmed that Raheem Sterling had been passed fit after a recent scare, but also revealed that Aymeric Laporte and Nathan Ake are injured, while star striker Sergio Aguero and youngster Cole Palmer are isolating after coming into contact with people who have tested positive for Coronavirus.
Click and scroll through the pages below to see our Man City predicted starting XI ahead of Wednesday’s clash:
1. Ederson
The Brazilian stopper has missed out on City's last few matches, but should be back between the sticks on Wednesday. (Photo by Clive Brunskill/Getty Images) Photo: Clive Brunskill
2. Joao Cancelo
Cancelo has been inspired form of late, and is likely to start at right-back. (Photo by OLI SCARFF/AFP via Getty Images) Photo: OLI SCARFF
3. Ruben Dias
The Portuguese centre-back has been a revelation since arriving in England. A spot at centre-back is his to lose. (Photo by PETER POWELL/POOL/AFP via Getty Images) Photo: PETER POWELL
4. John Stones
Stones has been reborn in recent weeks. Great news for England, not so great news for Brighton. It would be a major shock if he didn't keep his place at the heart of defence. (Photo by Alex Livesey/Getty Images) Photo: Alex Livesey